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Select item 43582821.

A Parallel Quadruplex DNA Is Bound Tightly but Unfolded Slowly by Pif1 Helicase

Alicia K. Byrd, Kevin D. Raney

J Biol Chem. 2015 Mar 6; 290(10): 6482–6494. Published online 2015 Jan 14. doi: 10.1074/jbc.M114.630749

PMCID:: PMC4358282

Article PDF–3.2M

Select item 50629722.

G-quadruplex recognition and remodeling by the FANCJ helicase

Colin G. Wu, Maria Spies

Nucleic Acids Res. 2016 Oct 14; 44(18): 8742–8753. Published online 2016 Jun 24. doi: 10.1093/nar/gkw574

PMCID:: PMC5062972

Article PDF–2.5M

Select item 62408673.

Pif1 helicase unfolding of G-quadruplex DNA is highly dependent on sequence and reaction conditions

Alicia K. Byrd, Matthew R. Bell, Kevin D. Raney

J Biol Chem. 2018 Nov 16; 293(46): 17792–17802. Published online 2018 Sep 26. doi: 10.1074/jbc.RA118.004499

PMCID:: PMC6240867

Article PDF–1.5M

Select item 47371414.

Tim/Timeless, a member of the replication fork protection complex, operates with the Warsaw breakage syndrome DNA helicase DDX11 in the same fork recovery pathway

Federica Calì, Sanjay Kumar Bharti, Roberta Di Perna, Robert M. Brosh, Jr, Francesca M. Pisani

Nucleic Acids Res. 2016 Jan 29; 44(2): 705–717. Published online 2015 Oct 25. doi: 10.1093/nar/gkv1112

PMCID:: PMC4737141

Article PDF–3.0M

Select item 68795345.

Structural basis for DNA unwinding at forked dsDNA by two coordinating Pif1 helicases

Nannan Su, Alicia K. Byrd, Sakshibeedu R. Bharath, Olivia Yang, Yu Jia, Xuhua Tang, Taekjip Ha, Kevin D. Raney, Haiwei Song

Nat Commun. 2019; 10: 5375. Published online 2019 Nov 26. doi: 10.1038/s41467-019-13414-9

PMCID:: PMC6879534

Article PDF–2.1M

Select item 47973046.

G-quadruplexes and helicases

Oscar Mendoza, Anne Bourdoncle, Jean-Baptiste Boulé, Robert M. Brosh, Jr, Jean-Louis Mergny

Nucleic Acids Res. 2016 Mar 18; 44(5): 1989–2006. Published online 2016 Feb 15. doi: 10.1093/nar/gkw079

PMCID:: PMC4797304

Article PDF–2.0M

Select item 92505687.

G4-quadruplex-binding proteins: review and insights into selectivity

Vanessa Meier-Stephenson

Biophys Rev. 2022 Jun; 14(3): 635–654. Published online 2022 Apr 20. doi: 10.1007/s12551-022-00952-8

PMCID:: PMC9250568

Article PDF–2.2M

Select item 47867238.

Yeast Helicase Pif1 Unwinds RNA:DNA Hybrids with Higher Processivity than DNA:DNA Duplexes

Shubeena Chib, Alicia K. Byrd, Kevin D. Raney

J Biol Chem. 2016 Mar 11; 291(11): 5889–5901. Published online 2016 Jan 5. doi: 10.1074/jbc.M115.688648

PMCID:: PMC4786723

Article PDF–2.7M

Select item 32568699.

Biochemical Characterization of Warsaw Breakage Syndrome Helicase

Yuliang Wu, Joshua A. Sommers, Irfan Khan, Johan P. de Winter, Robert M. Brosh, Jr.

J Biol Chem. 2012 Jan 6; 287(2): 1007–1021. Published online 2011 Nov 18. doi: 10.1074/jbc.M111.276022

PMCID:: PMC3256869

Article PDF–2.4M

Select item 291003710.

Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae

Aurèle Piazza, Jean-Baptiste Boulé, Judith Lopes, Katie Mingo, Eric Largy, Marie-Paule Teulade-Fichou, Alain Nicolas

Nucleic Acids Res. 2010 Jul; 38(13): 4337–4348. Published online 2010 Mar 11. doi: 10.1093/nar/gkq136

PMCID:: PMC2910037

Article PDF–5.5M

Select item 533971011.

Single-molecule studies reveal reciprocating of WRN helicase core along ssDNA during DNA unwinding

Wen-Qiang Wu, Xi-Miao Hou, Bo Zhang, Philippe Fossé, Brigitte René, Olivier Mauffret, Ming Li, Shuo-Xing Dou, Xu-Guang Xi

Sci Rep. 2017; 7: 43954. Published online 2017 Mar 7. doi: 10.1038/srep43954

PMCID:: PMC5339710

Article PDF–1.6M

Select item 745289612.

Warsaw Breakage Syndrome associated DDX11 helicase resolves G-quadruplex structures to support sister chromatid cohesion

Janne J. M. van Schie, Atiq Faramarz, Jesper A. Balk, Grant S. Stewart, Erika Cantelli, Anneke B. Oostra, Martin A. Rooimans, Joanna L. Parish, Cynthia de Almeida Estéves, Katja Dumic, Ingeborg Barisic, Karin E. M. Diderich, Marjon A. van Slegtenhorst, Mohammad Mahtab, Francesca M. Pisani, Hein te Riele, Najim Ameziane, Rob M. F. Wolthuis, Job de Lange

Nat Commun. 2020; 11: 4287. Published online 2020 Aug 27. doi: 10.1038/s41467-020-18066-8

PMCID:: PMC7452896

Article PDF–4.0M

Select item 415567713.

Mycobacterium tuberculosis DinG Is a Structure-specific Helicase That Unwinds G4 DNA: IMPLICATIONS FOR TARGETING G4 DNA AS A NOVEL THERAPEUTIC APPROACH

Roshan Singh Thakur, Ambika Desingu, Shivakumar Basavaraju, Shreelakshmi Subramanya, Desirazu N. Rao, Ganesh Nagaraju

J Biol Chem. 2014 Sep 5; 289(36): 25112–25136. Published online 2014 Jul 24. doi: 10.1074/jbc.M114.563569

PMCID:: PMC4155677

Article PDF–6.7M

Select item 1048054214.

ssDNA reeling is an intermediate step in the reiterative DNA unwinding activity of the WRN-1 helicase

Son Truong Le, Seoyun Choi, Seung-Won Lee, Hajin Kim, Byungchan Ahn

J Biol Chem. 2023 Sep; 299(9): 105081. Published online 2023 Jul 24. doi: 10.1016/j.jbc.2023.105081

PMCID:: PMC10480542

Article PDF–5.3M

Select item 298153415.

Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes

Yuliang Wu, Joshua A. Sommers, Avvaru N. Suhasini, Thomas Leonard, Julianna S. Deakyne, Alexander V. Mazin, Kazuo Shin-ya, Hiroyuki Kitao, Robert M. Brosh, Jr

Blood. 2010 Nov 11; 116(19): 3780–3791. Prepublished online 2010 Jul 16. doi: 10.1182/blood-2009-11-256016

PMCID:: PMC2981534

Article

Select item 697589516.

Prediction of the secondary structure of short DNA aptamers

Arina Afanasyeva, Chioko Nagao, Kenji Mizuguchi

Biophys Physicobiol. 2019; 16: 287–294. Published online 2019 Nov 29. doi: 10.2142/biophysico.16.0_287

PMCID:: PMC6975895

Article PDF–4.2M

Select item 615951617.

A minimal threshold of FANCJ helicase activity is required for its response to replication stress or double-strand break repair

Sanjay Kumar Bharti, Joshua A Sommers, Sanket Awate, Marina A Bellani, Irfan Khan, Lynda Bradley, Graeme A King, Yeonee Seol, Venkatasubramanian Vidhyasagar, Yuliang Wu, Takuye Abe, Koji Kobayashi, Kazuo Shin-ya, Hiroyuki Kitao, Marc S Wold, Dana Branzei, Keir C Neuman, Robert M Brosh, Jr

Nucleic Acids Res. 2018 Jul 6; 46(12): 6238–6256. Published online 2018 May 21. doi: 10.1093/nar/gky403

PMCID:: PMC6159516

Article PDF–7.2M

Select item 493318618.

Biochemical Characterization of the Human Mitochondrial Replicative Twinkle Helicase: SUBSTRATE SPECIFICITY, DNA BRANCH MIGRATION, AND ABILITY TO OVERCOME BLOCKADES TO DNA UNWINDING

Irfan Khan, Jack D. Crouch, Sanjay Kumar Bharti, Joshua A. Sommers, Sean M. Carney, Elena Yakubovskaya, Miguel Garcia-Diaz, Michael A. Trakselis, Robert M. Brosh, Jr.

J Biol Chem. 2016 Jul 1; 291(27): 14324–14339. Published online 2016 May 11. doi: 10.1074/jbc.M115.712026